A tandem Heck-aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines.
نویسندگان
چکیده
A palladacycle-catalyzed tandem Heck-intramolecular aza-Michael reaction protocol has been developed for the one-pot synthesis of 1-substituted isoindolines from N-unprotected 2-bromobenzylamines and acrylates with high yields.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 10 32 شماره
صفحات -
تاریخ انتشار 2012